Laboratory of
Bioprocesses Development

Dr Joel Sirois

Industrial partnership:

Vacci-Vet

• Our experience with industrial production help us to quickly identify our partners requirements then to develop efficient strategies to fulfill there expectations.

• Our multidisciplinary expertise and state-of-the-art facilities enable us to efficiently realize with professionalism different type of project we were entrusted.

Examples of projects realized

Optimizing cell culture performances:

• External induction and biocatalysts (ex.: elicitation of new production pathways)

• Culture medium composition (ex.: nitrogen sources and concentrations)

• Culture parameters (ex.: pH, temperature, mixing)

Characterizing bio-reactions:

• Production kinetics (ex.: production rate of active compounds)

• Nutrient kinetics (ex.: nutrient absorption and consumption rate)

• Cell metabolism (ex.: mass accumulation rate, division rate , bioconversion rates)

• Culture medium formulation

Developing operational strategies:

• Bioprocess development and integration (ex.: Identification and validation of production and purification steps)

• Control strategies and algorithms (ex.: PID, Adaptatif, Prédictif)

Scaling bioprocesses:

• Scale-up (ex.: from lab to pilot scale)

• Scale-down (ex.: process intensification)